Combining Proven Technologies to Deliver G Group-Level Resolution Genotyping
A growing number of laboratories are evaluating next-generation sequencing (NGS) because it provides allele-level typing with minimal ambiguity. However, concerns remain over turnaround time, complexity of the workflow and data analysis, and cost of NGS consumables.
G-Res combines sequenced based typing (SBT) and reverse sequence specific oligonucleotide typing (rSSO); two technologies currently available in many laboratories; to produce single genotypes at G level resolution.
G-Res combines sequence-based typing with phasing probe hybridization techniques to deliver high resolution genotyping of HLA-A, -B, -C and –DRB1 loci. Data from the DNA sequencing and the probe hybridization pathways are merged and analyzed in HLA Fusion™ Research software. Genotype assignments from each pathway are compared to report G-group resolution results.
Features & Benefits
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