The AT1R and anti-ETAR antibody assays detect biomarker antibodies that form against angiotensin II type 1 receptors (AT1R) and endothelin receptors type A (ETAR). They offer a new approach to transplant research testing at a non-HLA level.
AT1R is found in most major organs, suggesting the importance of anti-AT1R antibodies as a possible biomarker for solid organ transplants and Antibody Mediated Rejection.
The ETAR assay is designed to detect antibodies that form agains endothelin receptor type A (anti-ETAR), a G protein-coupled receptor. By detecting biomarker antibodies that form anti-ETAR, this assay offers a new approach to transplant research at a non-HLA level.