Bead-based Multiplexing Assay for PRA Screening
As the leader in HLA antibody screening, One Lambda offers the largest portfolio of assays for low- to high-resolution detection. Our selection of reagents for the LABScreen line of products are powered by Luminex® xMAP® technology—a microbead platform used to deliver multiplex antibody assays in high-PRA patients. These single antigen-bead based assays allow for precise determination of antibody profiles against HLA, MICA or HNA.
LABScreen assays produce trusted results, with consistency and high sensitivity, and are considered to be the gold standard in HLA antibody detection.
assay for PRA Screening
LABScreen products use a panel of color-coded microbeads, coated with purified HLA antigens. Up to 100 different beads can be combined in one suspension in a single test. The serum is incubated with LABScreen beads. Any HLA antibodies in the serum bind to the antigens and are labeled with PE-conjugated goat anti-human IgG. The LABScan™ 100 or LABScan3D™ systems detect fluorescent emission of PE from each bead, allowing nearly real-time data acquisition.
LABScreen Autoantibody assays detect a wide array of biomarker including tubulin and perlecan antibodies following a familiar workflow and analysis algorithm.
For Research Use Only. Not for use in diagnostic procedures.
ExPlex now offers an extended HLA antibody panel in a single-well setup! Paired with the original LABScreen SABs, ExPlex provides cutting-edge capabilities with a total of 151 Class I and 119 Class II Common and Well-Documented alleles.
The powerful next step for HLA donor specific antibody (DSA) testing is available with the new ExPlex!
For In Vitro Diagnostic Use.